Isotopically Labeled Compounds
Medchemexpress LLC Acetylcholine-d9 bromide | 93449-32-2 | 98.9% | 1 MG
Acetylcholine-d9 (bromide) is the deuterium labeled Acetylcholine bromide.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Clemastine-d5 fumarate | 14976-57-9 | 99.5% | 1 MG
Clemastine-d5 fumarate | 14976-57-9 | 99.5% | 1 MG
Cayman Chemical CystathIonIn-d4 500ug
An internal standard for the quantification of cystathionine by GC- or LC-MS
Medchemexpress LLC Isoxsuprine-d6 (hydrochloride) | 2706004-35-3 | 99.9% | 500 UG
Isoxsuprine-d6 (hydrochloride) is the deuterium-labeled Isoxsuprine hydrochloride. Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with Kis of 13.65 μΜ and 3.48 μΜ for myometrial and placental beta-adrenergic receptors, respectively. It is also an NMDA receptor antagonist.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Butylparaben-d4 | 1219798-67-0 | 98.6% | 1 MG
Butylparaben-d4 is the deuterium labeled Butylparaben, an organic compound that has been successfully used as an antimicrobial preservative in cosmetics, medication suspensions, and as a flavoring additive in food.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes into drug molecules for quantitation during drug development.
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Classified as an isotope-labeled compound and an internal standard for food.
Medchemexpress LLC Crisaborole-d4 | 2268785-42-6 | 98.8% | 255.07 | 1 ML
Crisaborole-d4 is deuterium labeled Crisaborole, a potent inhibitor of PDE4 and cytokine release. It inhibits PDE4 with an IC50 of 0.49 μM. This compound is suitable for use as a tracer and an internal standard for quantitative analysis, leveraging the potential of deuteration to affect pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Potent inhibitor of PDE4 and cytokine release
- Suitable as a tracer
- Suitable as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC (Rac)-DPPC-d6 | 82765-17-1 | 98.0% | 740.08 | 10 MG
This product is a deuterated labeled phosphoglyceride used in lipid research.
- Suitable for lipid research applications.
Medchemexpress LLC 5Z,8Z,11Z,14Z-Eicosatetraenoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid | 2692624-11-4 | 98.0% | 315.53 | 100 MG
Arachidonic acid-d11 is the deuterium labeled Arachidonic acid, an essential fatty acid and a major constituent of biomembranes. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. This product has been tested and complies with the given specifications. Solution, -20°C, 2 years.
- Target: Endogenous Metabolite; Isotope-Labeled Compounds
- Pathway: Metabolic Enzyme/Protease; Others
- Appearance: Colorless to light yellow (Liquid)
Medchemexpress LLC Hydroxyzine-d4 dihydrochloride | 1219805-91-0 | 98.0% | 5 MG
Hydroxyzine-d4 dihydrochloride is a deuterium labeled form of Hydroxyzine dihydrochloride. This orally active benzodiazepine antihistamine agent functions as a histamine H1-receptor and serotonin antagonist. It possesses anxiolytic effects and is utilized in research for generalized anxiety disorder.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules as tracers for quantitation during drug development.
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs.
Cayman Chemical 25-hydroxy VItamIn D2-d6 1mg
An internal standard for the quantification of 25-hydroxy vitamin D2 by GC- or LC-MS
Cayman Chemical PAF C-16-d4 1mg
An internal standard for the quantification of PAF C-16 by GC- or LC-MS.
Medchemexpress LLC 2,4-dimethylaniline-d6 | 1071170-27-8 | MFCD22565800 | 99.0% | 127.22 | C8H5D6N | 5 MG
2,4-Xylidine-d6 is the deuterium-labeled analogue of 2,4-xylidine (2,4-dimethylaniline) used as a stable isotope standard and tracer in analytical chemistry and mass spectrometry. It is supplied for laboratory research use only.
- Deuterium-labeled internal standard for mass spectrometry and tracer studies.
- Molecular formula C8H5D6N; molecular weight 127.22.
- CAS number 1071170-27-8.
- Supplied in small preweighed quantities suitable for analytical standards.
- High purity (≈99.0%) based on certificate of analysis.
Apexbio Technology LLC Sphingosine-1-phosphate 26993-30-6 1mg
Sphingosine-1-phosphate (CAS 26993-30-6) is an endogenous signaling lipid functioning as a second messenger and ligand for the G-protein-coupled receptor S1PR1 (also called EDG1) It modulates diverse cellular processes including proliferation survival migration and vascular morphogenesis via activation of downstream pathways such as ERK-1/2 kinase and Gi protein-mediated signaling In cell-based assays S1P exhibits high-affinity binding (Kd 8 1 nM) to S1PR1 and induces calcium mobilization with an EC50 of approximately 2 nM Due to its roles in platelet function cell survival and vascular biology S1P is widely investigated in cell signaling research and therapeutic development
Cayman Chemical 2-DeoxyurIdIn-d2 1mg
An internal standard for the quantification of 2’-deoxyuridine by GC- or LC-MS